Alzheimer: descubriendo lo invisible

2019-07-04T13:45:24+02:00Categories: Computer Vision|Tags: |0 Comments

Alzheimer´s disease causes symptoms such as memory loss, disorientation or mood swings in those suffering from it, but, what exactly changes in the brain and how can we improve its detection? Magnetic resonance imaging (MRI) opens the possibility of examining the structure, the metabolism or the functionality of the brain and thereby, numerous analysis tools have been developed to understand and extract the information they carry. One of the most common techniques is “Voxel-based morphometry” or VBM (Ashburner and Friston, 2000), used to identify brain regional atrophy by statistically comparing a group of patients with a group of controls. Figure 1 describes the steps involved in a VBM analysis. Figure 1: Steps of a VBM analysis. VBM studies to date have exploited T1-weighted MRIs, which were designed to enhance the MRI signal contrast between grey and white matter tissues (Figure 2). They are therefore suitable for detecting [...]